Welcome to the Rubin Lab
Tuberculosis is the leading infectious killer of adults worldwide. Despite over a century of research on the causative organism, Mycobacterium tuberculosis, we still have a very poor understanding of tuberculous infections. Our goal is to better understand the basic biology of this pathogen and to develop new therapeutic strategies.
Our research focuses on three areas. We study the fundamental cell biology of the organism, including central processes such as cell wall metabolism, cell growth and translation. We also investigate antibiotics – how they work and how we can make new ones. Finally, we build the tools to study mycobacteria both in vitro and during infection.